Complete microbial genomes for public health in Australia and the Southwest Pacific

Microb Genom. 2020 Dec;6(12):mgen000471. doi: 10.1099/mgen.0.000471. Epub 2020 Nov 12.

Abstract

Complete genomes of microbial pathogens are essential for the phylogenomic analyses that increasingly underpin core public health laboratory activities. Here, we announce a BioProject (PRJNA556438) dedicated to sharing complete genomes chosen to represent a range of pathogenic bacteria with regional importance to Australia and the Southwest Pacific; enriching the catalogue of globally available complete genomes for public health while providing valuable strains to regional public health microbiology laboratories. In this first step, we present 26 complete high-quality bacterial genomes. Additionally, we describe here a framework for reconstructing complete microbial genomes and highlight some of the challenges and considerations for accurate and reproducible genome reconstruction.

Keywords: genomics; public health microbiology; reference genomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Australia
  • Bacteria / classification*
  • Bacteria / genetics
  • Databases, Genetic
  • Genome, Bacterial*
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Phylogeny
  • Public Health
  • Whole Genome Sequencing / methods*